Beta-Alanine- Non-essential amino acid beta-alanine is the only naturally occurring beta-amino acid. It is classified as a non-proteinogenic amino acid as it is not involved in the process of protein synthesis. Beta-alanine are obtained by ingesting dipeptides (carnosine, anserine and balenine) which are found in protein rich foods like chicken, beef, pork and fish. Most of the beta-alanine we ingest is through didpeptide carnosine since the other two are not found in our typical diets. However apart from the diet, beta-alanine is also synthesized in the liver from the catabolism of pyrimidine nucleotides. Beta-alanine is beneficial for those trying to gain muscle mass and increase strength. It is also useful for athletes who are looking for muscle strength, power and endurance. Since it is so useful for muscle development, several supplements used by athletes have beta alanine as a primary component.

Betaine HCL, or betaine hydrochloride, is not an essential nutrient, but it helps in absorption of proteins, vitamin B12, iron and calcium and helps in the digestive tract with the protein and fat breaking up abilities. It is a supplemental source of hydrochloric acid, with a low pH level. Besides the obvious use against indigestion and heartburn, other uses have been proclaimed for betaine HCL, such as lowering the homocysteine level, helping with thyroid conditions and others. With progressing age, hydrochloric acid and digestive enzymes may decrease, with a poor digestion as a result. With betaine HCL, when taken at the beginning of a meal, proper digestion can be accomplished. Betaine HCL is most commonly provided with the addition of pepsin, a digestive enzyme.

Creatine Alpha-Ketoglutarate , also called creatine AKG is formed by binding together AKG and creatine molecules. Alpha-ketoglutarate is a precursor of glutamine, meaning this supplement provides both glutamine and creatine. The vital benefit is that the intestines absorb AKG more easily, thus preventing diarrhea that most of the bodybuilders experience when they consume creatine monohydrate. Another important benefit of creatine AKG is that AKG crosses readily into muscle tissue without creatine transporters. Creatine and AKG are also utilized in the Krebs cycle -- an aerobic energy-producing pathway -- that is used to replenish the levels of quick energy in muscle cells in between workout sets. Because creatine ensures quick energy for completing more reps, and AKG assists in restoring energy levels between sets, combination of the two is a very effective in keeping energy and strength levels high during workout.

Creatine Ethyl Ester is an organic compound formed by the reaction of alcohols and carboxylic acid. The standard creatine monohydrate is effective in increasing the muscle strength, lean muscle and endurance. Creatine ethyl ester is absorbed by the ability of the cells as the body does not absorb it properly. This is the reason that creatine is taken in large dosages. Creatine ethyl ester is a monohydrate associated with ester. This ester has the significance as it is found in the animals fat tissue. Creatine supplements are blended with protein powder. However, if it is taken for a longer period, the body stops producing it naturally and completely depends on the supplement. The creatine monohydrate shows no reports having side effects. Women also take creatine, but consulting the doctor is recommended. Ethyl ester decreases the amount of retained water as it is made with typical fatty acids that occur naturally. Hence, less creatine is stored as water weight out of the nutrient pocket.

Di-Creatine Orotate is the combination of ordinary creatine with Orotic Acid. It is used as a performance enhancement supplement by athletes and body builders to increase muscle gains, muscle strength and stamina. It is believed to offer greater ATP formation and absorption. Di-Creatine oratate increases ATP formation by providing phosphoribosylpyrophosphate, Uridine Monophosphate and by elevation of intracellular glycogen stores, all of these contribute to ATP formation. In experiment on rats it induced increase of very-low-density-lipoproteins, VLDL (fats) in the rats, however Manufacturers claim that the supplement is completely safe for human as the increase in VLDL (fats) is very low.

Glycerol Monostearate also referred to as GMS. It is that fat that is formed when glycerol is esterified with stearic acid. It occurs in the body naturally as a by-product of fats and it can also be found in certain fatty foods. Glycerol Monostearate increases the endurance by retaining water in the body. They glycerol helps lower the body temperature and delay fatigue while increasing the performance. It also helps in reducing the acidity that forms in the muscle. It also improves the absorption of other supplements by helping in the delivery the nutrients in the system. It is also ideal, in losing weight because it enhances the metabolism.

Glycocyamine was sought after because as much as a quarter of the world’s population is unable to supplement creatine, more accurately, the supplementation of regular creatine monohydrate had no effect whatsoever. Glycocyamine is a creatine metabolite, missing just a methyl group. Glycocyamine is guanidinoacetic acid and creatine is methylguanidinoacetic acid. Interestingly enough, glycocyamine is processed by the liver and metabolized into creatine, which allowed the rest of the world to supplement creatine as well. Unfortunately the supplementation of glycocyamine also meant that many methyl groups otherwise needed by the body would be now used up by the synthesis of creatine. For that reason it is generally recommended to supplement glycocyamine together with betaine, in order to provide enough methyl groups for all purposes. The commonly suggested ration is four parts betaine, one part glycocyamine, hence a four to one ratio.

R-Alpha Lipoic Acid is a life-extending super antioxidant that functions both as fat and water soluble that easily crosses cell membranes. It potently serves to regenerate other antioxidants such as Vitamin C, Vitamin E, and glutathione. Glutathione is the most important water-soluble antioxidant. R-Alpha Lipoic Acid improves mitochondrial functions and metabolic rates. It also decreases oxidative damage while providing protection against the toxic effects of arsenic, cadmium, and mercury. It acts as an anti-aging nutrient via both its antioxidant properties and its antiglycation properties. It is very beneficial in treating diseases involving the liver as well as Type II Diabetes, by improving overall control of blood sugar and reducing blood sugar and insulin levels.