Caffeine is a methylated xenthine discovered in 1819 by Friedrich Ferdinand Runge, a German chemist. Sources of Caffeine include beans, fruit and leaves of some plants. Caffeine available for human consumption is most commonly extracted from the coffee plant cherries and tea bush leaves, as well as foods and drinks that contain products derived from the kola nut. Caffeine can temporarily reduce the sensation of being tired; however, this does not mean that it eliminates the need for sleep. Generally, twenty five to fifty milligrams of caffeine is enough for most consumers to report an increase in alertness and arousal. Caffeine should be not be consumed by those with fecal incontinence as it relaxes the internal anal sphincter muscles.

Citrus Aurantium, More commonly called "bitter orange", which is taken from unripe oranges. Research shows that citrus aurantium can increase the metabolic rate without affecting heart rate or blood pressure, breaks down fat, burns calories and may act as an appetite suppressant.

Garcinia Cambogia is helpful for weight loss as it suppresses accumulation of body fats. It promotes fat oxidation, increases serotonin release and its availability in brain, normalizes lipid profiles and reduces serum leptin levels in overweight people. Garcinia cambogia extract improves mucosal defensive mechanisms in the stomach and, so, is a good protective agent against gastric ulcers. It reduces both the volume and acidity of gastric juice. It acts as an appetite suppressant and also enhances metabolism. Garcinia cambogia can be helpful for people who attempt to have a low carb diet. It helps improve energy levels and strengthen the immune system. Garcinia cambogia extract can increase mucosal defense means in stomach, thus helping with gastric ulcers. It can decrease stomach acidity, and increase defensive properties on gastric juices.

Ginger Root- Ginger is a very popular spice and has been used for culinary purposes for ages. Besides the widespread use in the cuisine of many nations, several traditional medicines, including the Indian and Chinese medicinal practices, have used this Zingiber officinale, as the Latin name goes, for its pain relieving, anti allergenic and anti inflammatory activities. Further uses have been noted for treatment of various ailments of the digestive tract, such as diarrhea and nausea, but also as general stomach settlers. While the use of the ginger root extract has been used in ginger beer and ginger ale beverages, the use as dietary supplement or component in nutritional supplement concoctions is relatively recent. The volatile oils of the ginger root extract have been noted for the antibacterial, analgesic, sedative and antipyretic properties.

Hoodia Gordonii is widely thought of as an appetite suppressant; however, there have not been sufficient studies to support this theory.

Vitamin B5 is widely used for its effective use to treat acne. It is also used to relieve pain caused by rheumatoid arthritis and to relieve morning stiffness. Deficiency of Vitamin B5 is rare but can cause nausea, fatigue, headache and skin abnormalities. It plays a key role in the metabolism of carbohydrates and fats to release energy. It is also vital in antibody formation which helps in building immune system and preventing infections.

White Willow Bark, or Salix alba, is a willow commonly found in Europe and adjacent parts of western and central Asia. The bark of the White Willow has been used for centuries against fevers and to ease pains and aches. Already Hippocrates wrote about the White Willow bark powder two thousand five hundred years ago. The active ingredient of the White Willow bark is called salicin, a relative to aspirin and chemical derivative of the salicylic acid. When ingested, salicin is converted to salicylic acid, a beta hydroxy acid. As a nutritional supplement, White Willow products are being propagated as weight loss additives, whereby the scientific community has yet to provide any corroboration to this allegation. Besides the well known anti inflammatory characteristics, any other uses have not been approved by the FDA.